Ethena Replaces Aerodrome
The biggest change came in Grayscale’s DeFi Fund. Following the CoinDesk DeFi Select Index methodology, the firm sold AERO and portions of other existing holdings to purchase $ENA.
As of May 1, 2026, the fund holdings stood at:
- Uniswap (UNI) – 35.22%
- Aave (AAVE) – 21.36%
- Ondo (ONDO) – 19.83%
- Ethena ($ENA) – 13.59%
- Curve (CRV) – 5.27%
- Lido DAO (LDO) – 4.73%
Smart Contract Fund Stays Focused on Layer 1s
Grayscale also adjusted the weightings of its Smart Contract Fund using the CoinDesk Smart Contract Platform Select Capped Index methodology. Unlike the DeFi Fund, no assets were removed or added.
The updated allocations are:
- Ethereum (ETH) – 30.14%
- Solana (SOL) – 29.69%
- Cardano (ADA) – 17.96%
- Avalanche (AVAX) – 7.69%
- Hedera (HBAR) – 7.41%
- Sui (SUI) – 7.11%
The allocation shows Grayscale still heavily favors established smart contract ecosystems led by Ethereum and Solana.
What This Signals for the Market
These updates give a simple look into where institutional investors believe crypto is heading. Grayscale appears to be betting more on DeFi projects connected to stablecoins, yield, and tokenized assets rather than only trading platforms.
At the same time, the company is still keeping strong exposure to big blockchain ecosystems like Ethereum and Solana, which continue to dominate developer activity and liquidity in crypto markets.
Overall, rebalances like this reflect where capital is rotating. The question is whether flows follow or lag.